Featured Papers
The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes
Science
Tran N-H*, Carter SD*, De Maziére A, Ashkenazi A, Klumperman J, Walter P+, Jensen GJ+
Tran N-H*, Carter SD*, De Maziére A, Ashkenazi A, Klumperman J, Walter P+, Jensen GJ+
A cryo–electron tomography workflow reveals protrusion-mediated shedding on injured plasma membrane
Science Advances
Mageswaran SK, Yang WY+, Chakrabarty Y, Oikonomou CM, Jensen GJ+
Mageswaran SK, Yang WY+, Chakrabarty Y, Oikonomou CM, Jensen GJ+
Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography
Science Advances
Zhang X, Carter SD, Singla J, White KL, Butler PC, Stevens RC+, Jensen GJ+
Zhang X, Carter SD, Singla J, White KL, Butler PC, Stevens RC+, Jensen GJ+
Correlated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivo
PNAS
Carter SD, Mamede JI, Hope TJ, Jensen GJ
Carter SD, Mamede JI, Hope TJ, Jensen GJ
CryoEM structure of the type IVa pilus secretin required for natural competence in Vibrio cholerae
Nature Communications
Weaver SJ, Ortega DR, Sazinsky MH, Dalia TN, Dalia AB, Jensen GJ
Weaver SJ, Ortega DR, Sazinsky MH, Dalia TN, Dalia AB, Jensen GJ
Repurposing a chemosensory macromolecular machine
Nature Communications
Ortega DR, Yang W, Subramanian P, Mann P, Kjær A, Chen S, Watts KJ, Pirbadian A, Collins DA, Kooger R, Kalyuzhnaya MG, Ringgaard S, Briegel A+, Jensen GJ+
Ortega DR, Yang W, Subramanian P, Mann P, Kjær A, Chen S, Watts KJ, Pirbadian A, Collins DA, Kooger R, Kalyuzhnaya MG, Ringgaard S, Briegel A+, Jensen GJ+
In vivo structure of the Legionella type II secretion system by electron cryotomography
Nature Microbiology
Ghosal D, Kim KW, Zheng H, Kaplan M, Truchan HK, Lopez AE, McIntire IE, Vogel JP, Cianciotto NP, Jensen GJ
Ghosal D, Kim KW, Zheng H, Kaplan M, Truchan HK, Lopez AE, McIntire IE, Vogel JP, Cianciotto NP, Jensen GJ
In situ imaging of the bacterial flagellar motor disassembly and assembly processes
EMBO Journal
Kaplan M, Subramanian P, Ghosal D, Oikonomou CM, Pirbadian S, Starwalt-Lee R, Mageswaran SK, Ortega DR, Gralnick JA, El-Naggar MY, Jensen GJ
Kaplan M, Subramanian P, Ghosal D, Oikonomou CM, Pirbadian S, Starwalt-Lee R, Mageswaran SK, Ortega DR, Gralnick JA, El-Naggar MY, Jensen GJ
Molecular architecture, polar targeting and biogenesis of the Legionella Dot/Icm T4SS
Nature Microbiology
Ghosal D*, Jeong KC*, Chang Y-W, Gyore J, Teng L, Gardner A, Vogel JP+, Jensen GJ+
Ghosal D*, Jeong KC*, Chang Y-W, Gyore J, Teng L, Gardner A, Vogel JP+, Jensen GJ+
Simulations suggest a constrictive force is required for Gram-negative bacterial cell division
Nature Communications
Nguyen LT, Oikonomou CM, Ding HJ, Kaplan M, Yao Q, Chang Y-W, Beeby M, Jensen GJ
Nguyen LT, Oikonomou CM, Ding HJ, Kaplan M, Yao Q, Chang Y-W, Beeby M, Jensen GJ
Rapid tilt-series acquisition for electron cryotomography
Journal of Structural Biology
Chreifi G*, Chen S*, Metskas LA, Kaplan M, Jensen GJ
Chreifi G*, Chen S*, Metskas LA, Kaplan M, Jensen GJ
Programmed secretion arrest and receptor-triggered toxin export during antibacterial contact-dependent growth inhibition
Cell
Ruhe ZC*, Subramanian P*, Song K*, Nguyen JY, Stevens TA, Low DA, Jensen GJ+, Hayes CS+
Ruhe ZC*, Subramanian P*, Song K*, Nguyen JY, Stevens TA, Low DA, Jensen GJ+, Hayes CS+
In vivo structures of the Helicobacter pylori cag type IV secretion system
Cell Reports
Chang Y-W*, Shaffer CL*, Rettberg LA, Ghosal D, Jensen GJ
Chang Y-W*, Shaffer CL*, Rettberg LA, Ghosal D, Jensen GJ
Ultrastructure of Shewanella oneidensis MR-1 nanowires revealed by electron cryotomography
PNAS
Subramanian P*, Pirbadian S*, El-Naggar MY+, Jensen GJ+
Subramanian P*, Pirbadian S*, El-Naggar MY+, Jensen GJ+
Structure of the fission yeast actomyosin ring during constriction
PNAS
Swulius MT*, Nguyen LT*, Ladinsky MS, Ortega DR, Aich S, Mishra M, Jensen GJ
Swulius MT*, Nguyen LT*, Ladinsky MS, Ortega DR, Aich S, Mishra M, Jensen GJ
In vivo structures of an intact type VI secretion system revealed by electron cryotomography
EMBO Reports
Chang Y-W, Rettberg LA, Ortega DR, Jensen GJ
Chang Y-W, Rettberg LA, Ortega DR, Jensen GJ
Short FtsZ filaments can drive asymmetric cell envelope constriction at the onset of bacterial cytokinesis
The EMBO Journal
Yao Q, Jewett AI, Chang Y-W, Oikonomou CM, Beeby M, Iancu CV, Briegel A, Ghosal D, Jensen GJ
Yao Q, Jewett AI, Chang Y-W, Oikonomou CM, Beeby M, Iancu CV, Briegel A, Ghosal D, Jensen GJ
Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography
Nature Microbiology
Chang Y-W, Kjaer A, Ortega DR, Kovacikova G, Sutherland JA, Rettberg LA, Taylor RK, Jensen GJ
Chang Y-W, Kjaer A, Ortega DR, Kovacikova G, Sutherland JA, Rettberg LA, Taylor RK, Jensen GJ
Architecture of the type IVa pilus machine
Science
Chang Y-W, Rettberg LA, Treuner-Lange A, Iwasa J, Sogaard-Andersen L, Jensen GJ
Chang Y-W, Rettberg LA, Treuner-Lange A, Iwasa J, Sogaard-Andersen L, Jensen GJ
Coarse-grained simulations of bacterial cell wall growth reveal that local coordination alone can be sufficient to maintain rod shape
PNAS
Nguyen LT, Gumbart JC, Beeby M, Jensen GJ
Nguyen LT, Gumbart JC, Beeby M, Jensen GJ
Correlated cryogenic photoactivated localization microscopy and cryo-electron tomography
Nature Methods
Chang YW, Chen S, Tocheva EI, Treuner-Lange A, Löbach S, Søgaard-Andersen L, Jensen GJ
Chang YW, Chen S, Tocheva EI, Treuner-Lange A, Löbach S, Søgaard-Andersen L, Jensen GJ
Marine tubeworm metamorphosis induced by arrays of bacterial phage tail-like structures
Science
Shikuma NJ*, Pilhofer M*, Weiss GL, Hadfield MG+, Jensen GJ+, Newman DK+
Shikuma NJ*, Pilhofer M*, Weiss GL, Hadfield MG+, Jensen GJ+, Newman DK+
Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ
Nature Communications
Pilhofer M*, Aistleitner K*, Biboy J, Gray J, Kuru E, Hall E, Brun YV, VanNieuwenhze MS, Vollmer W, Horn M+, Jensen GJ+
Pilhofer M*, Aistleitner K*, Biboy J, Gray J, Kuru E, Hall E, Brun YV, VanNieuwenhze MS, Vollmer W, Horn M+, Jensen GJ+
Electron cryotomography of ESCRT assemblies and dividing Sulfolobus cells suggests that spiraling filaments are involved in membrane scission
Molecular Biology of the Cell
Dobro MJ, Samson RY, Yu Z, McCullough J, Ding HJ, Chong PL, Bell SD, Jensen GJ
Dobro MJ, Samson RY, Yu Z, McCullough J, Ding HJ, Chong PL, Bell SD, Jensen GJ
Architecture and assembly of the Gram-positive cell wall
Molecular Microbiology
Beeby M, Gumbart JC, Roux B, Jensen GJ
Beeby M, Gumbart JC, Roux B, Jensen GJ