Publications
Search by Year
Search by Category
2024
Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center
bioRXiv doi.org/10.1101/2024.09.12.612739
Wang, J., Wu, M., Magupalli, V., Dahlberg, P., Wu, H., and Jensen, G.
Wang, J., Wu, M., Magupalli, V., Dahlberg, P., Wu, H., and Jensen, G.
2023
Bdellovibrio predation cycle characterized at nanometre-scale resolution with cryo-electron tomography
Nature Microbiology /10.1038/s41564-023-01401-2
Kaplan, M., Chang, Y.-W., Oikonomou, C. M., Nicolas, W. J., Jewett, A. I., Kreida, S., Duta, P., Rettberg, L. A., Maggi, S., and Jensen, G. J.
Kaplan, M., Chang, Y.-W., Oikonomou, C. M., Nicolas, W. J., Jewett, A. I., Kreida, S., Duta, P., Rettberg, L. A., Maggi, S., and Jensen, G. J.
Structure and Function of the Dot/Icm T4SS
bioRxiv doi.org/10.1101/2023.03.22.533729
Dutka, P., Liu, Y., Maggi, Ghosal, D., Wang, J., Carter, S. D., Zhao, W., Vijayrajratnam, S., Vogel, J. P., and Jensen, G. J.
Dutka, P., Liu, Y., Maggi, Ghosal, D., Wang, J., Carter, S. D., Zhao, W., Vijayrajratnam, S., Vogel, J. P., and Jensen, G. J.
Cryo-EM structure of the Agrobacterium tumefaciens T4SS-associated T-pilus reveals stoichiometric protein-phospholipid assembly
Structure S0969-2126(23)00039 -4
Kreida, S., Narita, A., Johnson, M. D., Tocheva, E. I., Das, A., Ghosal, D., and Jensen, G. J.
Kreida, S., Narita, A., Johnson, M. D., Tocheva, E. I., Das, A., Ghosal, D., and Jensen, G. J.
2022
A cryogenic, coincident fluorescence, electron, and ion beam microscope
eLife
Boltje DB, Hoogenboom JP, Jakobi AJ, Jensen GJ, Jonker CTH, Kaag MJ, Koster AJ, Last MGF, de Agrela Pinto C, Plitzko JM, Raunser S, Tacke S, Wang Z, van der Wee EB, Wepf R, den Hoedt S
Boltje DB, Hoogenboom JP, Jakobi AJ, Jensen GJ, Jonker CTH, Kaag MJ, Koster AJ, Last MGF, de Agrela Pinto C, Plitzko JM, Raunser S, Tacke S, Wang Z, van der Wee EB, Wepf R, den Hoedt S
Subtomogram averaging for biophysical analysis and supramolecular context
Journal of Structural Biology: X
Metskas LA, Wilfong R, Jensen GJ
Metskas LA, Wilfong R, Jensen GJ
Cryo-EM structure of the Agrobacterium tumefaciens type IV secretion system-associated T-pilus reveals stoichiometric protein-phospholipid assembly
bioRxiv
Kreida S*, Narita A*, Johnson MD, Tocheva EI, Das A, Ghosal D+, Jensen GJ+
Kreida S*, Narita A*, Johnson MD, Tocheva EI, Das A, Ghosal D+, Jensen GJ+
Geometric effects in gas vesicle buckling under ultrasound
Biophysical Journal
Salahshoor H*, Yao Y*, Dutka P*, Nyström NN, Jin Z, Min E, Malounda D, Jensen GJ, Ortiz M, Shapiro MG
Salahshoor H*, Yao Y*, Dutka P*, Nyström NN, Jin Z, Min E, Malounda D, Jensen GJ, Ortiz M, Shapiro MG
Structural remodeling of Coxiella burnetii during its biphasic developmental cycle revealed by cryo-electron tomography
bioRxiv
Kaplan M*, Shepherd DC*, Vankadari N, Kim KW, Larson CL, Dutka P, Beare PA, Krzymowski E, Heinzen RA, Jensen GJ+, Ghosal D+
Kaplan M*, Shepherd DC*, Vankadari N, Kim KW, Larson CL, Dutka P, Beare PA, Krzymowski E, Heinzen RA, Jensen GJ+, Ghosal D+
Rubisco forms a lattice inside alpha-carboxysomes
Nature Communications
Metskas LA, Ortega D, Oltrogge LM, Blikstad C, Lovejoy DR, Laughlin TG, Savage DF, Jensen GJ
Metskas LA, Ortega D, Oltrogge LM, Blikstad C, Lovejoy DR, Laughlin TG, Savage DF, Jensen GJ
Archaic chaperone–usher pili self-secrete into superelastic zigzag springs
Nature
Pakharukova N*, Malmi H*, Tuittila M, Dahlberg T, Ghosal D, Chang Y-W, Myint SL, Paavilainen S, Knight SD, Lamminmäki U, Uhlin BE, Andersson M, Jensen G, Zavialov AV
Pakharukova N*, Malmi H*, Tuittila M, Dahlberg T, Ghosal D, Chang Y-W, Myint SL, Paavilainen S, Knight SD, Lamminmäki U, Uhlin BE, Andersson M, Jensen G, Zavialov AV
Discovery of a Novel Inner Membrane-Associated Bacterial Structure Related to the Flagellar Type III Secretion System
Journal of Bacteriology
Kaplan M, Oikonomou CM, Wood CR, Chreifi G, Ghosal D, Dobro MJ, Yao Q, Pal RR, Baidya AK, Liu Y, Maggi S, McDowall AW, Ben-Yehuda S, Rosenshine I, Briegel A, Beeby M, Chang Y-W, Shaffer CL, Jensen GJ
Kaplan M, Oikonomou CM, Wood CR, Chreifi G, Ghosal D, Dobro MJ, Yao Q, Pal RR, Baidya AK, Liu Y, Maggi S, McDowall AW, Ben-Yehuda S, Rosenshine I, Briegel A, Beeby M, Chang Y-W, Shaffer CL, Jensen GJ
Structure of Anabaena flos-aquae gas vesicles revealed by cryo-ET
bioRxiv
Dutka P, Metskas LA, Hurt RC, Salahshoor H, Wang T-Y, Malounda D, Lu G, Chou T-F, Shapiro MG+, Jensen GJ+
Highlighted in Nature Structural & Molecular Biology Vol. 30
Dutka P, Metskas LA, Hurt RC, Salahshoor H, Wang T-Y, Malounda D, Lu G, Chou T-F, Shapiro MG+, Jensen GJ+
Highlighted in Nature Structural & Molecular Biology Vol. 30
Dynamic structural adaptations enable the endobiotic predation of Bdellovibrio bacteriovorus
bioRxiv
Kaplan M*, Chang Y-W*, Oikonomou CM, Nicolas WJ, Jewett AI, Kreida S, Dutka P, Rettberg LA, Maggi S, Jensen GJ
Kaplan M*, Chang Y-W*, Oikonomou CM, Nicolas WJ, Jewett AI, Kreida S, Dutka P, Rettberg LA, Maggi S, Jensen GJ
Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks
Current Biology
Nicolas WJ, Faessler F, Dutka P, Schur FKM, Jensen GJ, Meyerowitz EM
Nicolas WJ, Faessler F, Dutka P, Schur FKM, Jensen GJ, Meyerowitz EM
Montage electron tomography of vitrified specimens
Journal of Structural Biology
Peck A, Carter SD, Mai H, Chen S, Burt A, Jensen GJ
Peck A, Carter SD, Mai H, Chen S, Burt A, Jensen GJ
Novel transient cytoplasmic rings stabilize assembling bacterial flagellar motors
EMBO Journal
Kaplan M, Oikonomou CM, Wood CR, Chreifi G, Subramanian P, Ortega DR, Chang Y-W, Beeby M, Shaffer CL, Jensen GJ
Kaplan M, Oikonomou CM, Wood CR, Chreifi G, Subramanian P, Ortega DR, Chang Y-W, Beeby M, Shaffer CL, Jensen GJ
UVC inactivation of pathogenic samples suitable for cryo-EM analysis
Communications Biology
Depelteau JS, Renault L, Althof N, Cassidy CK, Mendonça LM, Jensen GJ, Resch GP, Briegel A
Depelteau JS, Renault L, Althof N, Cassidy CK, Mendonça LM, Jensen GJ, Resch GP, Briegel A
2021
Nanoscale details of mitochondrial fission revealed by cryo-electron tomography
bioRxiv
Mageswaran SK*, Grotjahn DA*+, Zeng X, Barad BA, Medina M, Hoang MH, Dobro MJ, Chang Y-W, Xu M, Yang WY, Jensen GJ+
Mageswaran SK*, Grotjahn DA*+, Zeng X, Barad BA, Medina M, Hoang MH, Dobro MJ, Chang Y-W, Xu M, Yang WY, Jensen GJ+
A bacterial membrane sculpting protein with BAR domain-like activity
eLife
Phillips DA*, Zacharoff LA*, Hampton CM, Chong GW, Malanoski AP, Metskas LA, Xu S, Bird LJ, Eddie BJ, Miklos AE, Jensen GJ, Drummy LF, El-Naggar MY, Glaven SM
Phillips DA*, Zacharoff LA*, Hampton CM, Chong GW, Malanoski AP, Metskas LA, Xu S, Bird LJ, Eddie BJ, Miklos AE, Jensen GJ, Drummy LF, El-Naggar MY, Glaven SM
The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes
Science
Tran N-H*, Carter SD*, De Maziére A, Ashkenazi A, Klumperman J, Walter P+, Jensen GJ+
Tran N-H*, Carter SD*, De Maziére A, Ashkenazi A, Klumperman J, Walter P+, Jensen GJ+
The Atlas of Bacterial & Archaeal Cell Structure: an Interactive Open-Access Microbiology Textbook
Journal of Microbiology & Biology Education
Oikonomou CM, Jensen GJ
Oikonomou CM, Jensen GJ
In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography
eLife
Kaplan M, Chreifi G, Metskas LA, Liedtke J, Wood CR, Oikonomou CM, Nicolas WJ, Subramanian P, Zacharoff LA, Wang Y, Chang Y-W, Beeby M, Dobro M, Zhu Y, McBride MJ, Briegel A, Shaffer C, Jensen GJ
Kaplan M, Chreifi G, Metskas LA, Liedtke J, Wood CR, Oikonomou CM, Nicolas WJ, Subramanian P, Zacharoff LA, Wang Y, Chang Y-W, Beeby M, Dobro M, Zhu Y, McBride MJ, Briegel A, Shaffer C, Jensen GJ
Loss of the Bacterial Flagellar Motor Switch Complex upon Cell Lysis
mBio
Kaplan M, Tocheva EI, Briegel A, Dobro MJ, Chang Y-W, Subramanian P, McDowall AW, Beeby M, Jensen GJ
Kaplan M, Tocheva EI, Briegel A, Dobro MJ, Chang Y-W, Subramanian P, McDowall AW, Beeby M, Jensen GJ
Generation of ordered protein assemblies using rigid three-body fusion
PNAS
Vulovic I, Yao Q*, Park Y-J*, Courbet A, Norris A, Busch F, Sahasrabuddhe A, Merten H, Sahtoe DD, Ueda G, Fallas JA, Weaver SJ, Hsia Y, Langan RA, Plückthun A, Wysocki VH, Veesler D, Jensen GJ, Baker D
Vulovic I, Yao Q*, Park Y-J*, Courbet A, Norris A, Busch F, Sahasrabuddhe A, Merten H, Sahtoe DD, Ueda G, Fallas JA, Weaver SJ, Hsia Y, Langan RA, Plückthun A, Wysocki VH, Veesler D, Jensen GJ, Baker D
Challenges in solving structures from radiation-damaged tomograms of protein nanocrystals assessed by simulation
Acta Crystallographica Section D
Peck A, Yao Q, Brewster AS, Zwart PH, Heumann JM, Sauter NK, Jensen GJ
Peck A, Yao Q, Brewster AS, Zwart PH, Heumann JM, Sauter NK, Jensen GJ
Programmed Flagellar Ejection in Caulobacter crescentus Leaves PL-subcomplexes
Journal of Molecular Biology
Kaplan M, Wang Y, Chreifi G, Zhang L, Chang Y-W, Jensen GJ
Kaplan M, Wang Y, Chreifi G, Zhang L, Chang Y-W, Jensen GJ
A cryo–electron tomography workflow reveals protrusion-mediated shedding on injured plasma membrane
Science Advances
Mageswaran SK, Yang WY+, Chakrabarty Y, Oikonomou CM, Jensen GJ+
Mageswaran SK, Yang WY+, Chakrabarty Y, Oikonomou CM, Jensen GJ+
Rapid tilt-series method for cryo-electron tomography: Characterizing stage behavior during FISE acquisition
Journal of Structural Biology
Chreifi G, Chen S, Jensen GJ
Chreifi G, Chen S, Jensen GJ
Measuring gas vesicle dimensions by electron microscopy
Protein Science
Dutka P, Malounda D, Metskas LA, Chen S, Hurt RC, Lu GJ, Jensen GJ+, Shapiro MK+
Dutka P, Malounda D, Metskas LA, Chen S, Hurt RC, Lu GJ, Jensen GJ+, Shapiro MK+
Moltemplate: A Tool for Coarse-Grained Modeling of Complex Biological Matter and Soft Condensed Matter Physics
Journal of Molecular Biology
Jewett AI+, Stelter D, Lambert J, Saladi SM, Roscioni OM, Ricci M, Autin L, Maritan M, Bashusqeh SM, Keyes T, Dame RT, Shea J-E, Jensen GJ, Goodsell DS+
Jewett AI+, Stelter D, Lambert J, Saladi SM, Roscioni OM, Ricci M, Autin L, Maritan M, Bashusqeh SM, Keyes T, Dame RT, Shea J-E, Jensen GJ, Goodsell DS+
2020
In Situ Imaging and Structure Determination of Biomolecular Complexes Using Electron Cryo-Tomography
Methods in Molecular Biology: CryoEM
Kaplan M, Nicolas WJ, Zhao W, Carter SD, Metskas LA, Chreifi G, Ghosal D, Jensen GJ
Kaplan M, Nicolas WJ, Zhao W, Carter SD, Metskas LA, Chreifi G, Ghosal D, Jensen GJ
Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography
Science Advances
Zhang X, Carter SD, Singla J, White KL, Butler PC, Stevens RC+, Jensen GJ+
Zhang X, Carter SD, Singla J, White KL, Butler PC, Stevens RC+, Jensen GJ+
Simulations of Proposed Mechanisms of FtsZ-Driven Cell Constriction
Journal of Bacteriology
Nguyen LT, Oikonomou CM, Jensen GJ
Nguyen LT, Oikonomou CM, Jensen GJ
Structure of the Bacterial Cellulose Ribbon and Its Assembly-Guiding Cytoskeleton by Electron Cryotomography
Journal of Bacteriology
Nicolas WJ, Ghosal D, Tocheva EI, Meyerowitz EM, Jensen GJ
Nicolas WJ, Ghosal D, Tocheva EI, Meyerowitz EM, Jensen GJ
Correlated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivo
PNAS
Carter SD, Mamede JI, Hope TJ, Jensen GJ
Carter SD, Mamede JI, Hope TJ, Jensen GJ
CryoEM structure of the type IVa pilus secretin required for natural competence in Vibrio cholerae
Nature Communications
Weaver SJ, Ortega DR, Sazinsky MH, Dalia TN, Dalia AB, Jensen GJ
Weaver SJ, Ortega DR, Sazinsky MH, Dalia TN, Dalia AB, Jensen GJ
PilY1 and minor pilins form a complex priming the type IVa pilus in Myxococcus xanthus
Nature Communications
Treuner-Lange A, Chang Y-W, Glatter T, Herfurth M, Lindow S, Chreifi G, Jensen GJ, Søgaard-Andersen L
Treuner-Lange A, Chang Y-W, Glatter T, Herfurth M, Lindow S, Chreifi G, Jensen GJ, Søgaard-Andersen L
Effects of antimicrobial photodynamic therapy on antibiotic-resistant Escherichia coli
Photodiagnosis and Photodynamic Therapy
Garcez AS*+, Kaplan M*, Jensen GJ, Scheidt FR, Oliveira EM, Suzuki SS
Garcez AS*+, Kaplan M*, Jensen GJ, Scheidt FR, Oliveira EM, Suzuki SS
In situ structure and organisation of the type IX secretion system
bioRxiv
Gorasia DG*, Chreifi G*, Seers CA, Butler CA, Heath JE, Glew MD, McBride MJ, Subramanian P, Kjaer A, Jensen GJ+, Veith PD+, Reynolds EC+
Gorasia DG*, Chreifi G*, Seers CA, Butler CA, Heath JE, Glew MD, McBride MJ, Subramanian P, Kjaer A, Jensen GJ+, Veith PD+, Reynolds EC+
Repurposing a chemosensory macromolecular machine
Nature Communications
Ortega DR, Yang W, Subramanian P, Mann P, Kjær A, Chen S, Watts KJ, Pirbadian A, Collins DA, Kooger R, Kalyuzhnaya MG, Ringgaard S, Briegel A+, Jensen GJ+
Ortega DR, Yang W, Subramanian P, Mann P, Kjær A, Chen S, Watts KJ, Pirbadian A, Collins DA, Kooger R, Kalyuzhnaya MG, Ringgaard S, Briegel A+, Jensen GJ+
Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient
PNAS
Kaplan M, Sweredoski MJ, Rodrigues JPGLM, Tocheva EI, Chang Y-W, Ortega DR, Beeby M, Jensen GJ
Kaplan M, Sweredoski MJ, Rodrigues JPGLM, Tocheva EI, Chang Y-W, Ortega DR, Beeby M, Jensen GJ
Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells
Science Advances
Carter SD*, Hampton CM*, Langlois R*, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ+, Frank J+, Freyberg Z+
Carter SD*, Hampton CM*, Langlois R*, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ+, Frank J+, Freyberg Z+
2019
In vivo structure of the Legionella type II secretion system by electron cryotomography
Nature Microbiology
Ghosal D, Kim KW, Zheng H, Kaplan M, Truchan HK, Lopez AE, McIntire IE, Vogel JP, Cianciotto NP, Jensen GJ
Ghosal D, Kim KW, Zheng H, Kaplan M, Truchan HK, Lopez AE, McIntire IE, Vogel JP, Cianciotto NP, Jensen GJ
Bacterial swarming reduces Proteus mirabilis and Vibrio parahaemolyticus cell stiffness and increases β-lactam susceptibility
mBio
Auer GK, Oliver PM, Rajendram M, Lin T-Y, Yao Q, Jensen GJ, Weibel DB
Auer GK, Oliver PM, Rajendram M, Lin T-Y, Yao Q, Jensen GJ, Weibel DB
DDX-Interface: A factory of interoperable scientific gateways
Gateways 2019 (Conference)
James A, Chacon R, Buddenhagen J, Ortega DR, Rees-Lee P, Jensen G, James DR
James A, Chacon R, Buddenhagen J, Ortega DR, Rees-Lee P, Jensen G, James DR
Distinct chemotaxis protein paralogs assemble into chemoreceptor signaling arrays to coordinate signaling output
mBio
O’Neal L*, Gullett JM*, Aksenova A, Hubler A, Briegel A, Ortega D, Kjaer A, Jensen G, Alexandre G
O’Neal L*, Gullett JM*, Aksenova A, Hubler A, Briegel A, Ortega D, Kjaer A, Jensen G, Alexandre G
Qualitative analyses of polishing and precoating FIB milled crystals for MicroED
Structure
Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T
Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T
Regular Architecture (RegArch): A standard expression language for describing protein architectures
bioRxiv
Ortega DR, Jensen GJ
Ortega DR, Jensen GJ
In situ imaging of the bacterial flagellar motor disassembly and assembly processes
EMBO Journal
Kaplan M, Subramanian P, Ghosal D, Oikonomou CM, Pirbadian S, Starwalt-Lee R, Mageswaran SK, Ortega DR, Gralnick JA, El-Naggar MY, Jensen GJ
Kaplan M, Subramanian P, Ghosal D, Oikonomou CM, Pirbadian S, Starwalt-Lee R, Mageswaran SK, Ortega DR, Gralnick JA, El-Naggar MY, Jensen GJ
Fusion of DARPin to aldolase enables visualization of small protein by cryoEM
Structure
Yao Q*, Weaver SJ*, Mock J-Y, Jensen GJ
Yao Q*, Weaver SJ*, Mock J-Y, Jensen GJ
Molecular architecture, polar targeting and biogenesis of the Legionella Dot/Icm T4SS
Nature Microbiology
Ghosal D*, Jeong KC*, Chang Y-W, Gyore J, Teng L, Gardner A, Vogel JP+, Jensen GJ+
Ghosal D*, Jeong KC*, Chang Y-W, Gyore J, Teng L, Gardner A, Vogel JP+, Jensen GJ+
ETDB-Caltech: a blockchain-based distributed public database for electron tomography
PLOS One
Ortega DR, Oikonomou CM, Ding HJ, Rees-Lee P, Alexandria, Jensen GJ
Ortega DR, Oikonomou CM, Ding HJ, Rees-Lee P, Alexandria, Jensen GJ
Simulations suggest a constrictive force is required for Gram-negative bacterial cell division
Nature Communications
Nguyen LT, Oikonomou CM, Ding HJ, Kaplan M, Yao Q, Chang Y-W, Beeby M, Jensen GJ
Nguyen LT, Oikonomou CM, Ding HJ, Kaplan M, Yao Q, Chang Y-W, Beeby M, Jensen GJ
De novo structural pattern mining in cellular electron cryotomograms
Structure
Xu M, Singla J, Tocheva EI, Chang Y-W, Stevens RC, Jensen GJ, Alber F
Xu M, Singla J, Tocheva EI, Chang Y-W, Stevens RC, Jensen GJ, Alber F
In situ imaging and structure determination of bacterial toxin delivery systems using electron cryotomography
Methods in Molecular Biology
Ghosal D*, Kaplan M*, Chang Y-W, Jensen GJ
Ghosal D*, Kaplan M*, Chang Y-W, Jensen GJ
FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
eLife
Azubel M, Carter SD, Weiszmann J, Zhang J, Jensen GJ, Li Y, Kornberg RD
Azubel M, Carter SD, Weiszmann J, Zhang J, Jensen GJ, Li Y, Kornberg RD
Collection of continuous rotation MicroED data from ion beam-milled crystals of any size
Structure
Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T
Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T
The presence and absence of periplasmic rings in bacterial flagellar motors correlates with stator type
eLife
Kaplan M, Ghosal D, Subramanian P, Oikonomou CM, Kjaer A, Pirbadian S, Ortega DR, Briegel A, El-Naggar MY, Jensen GJ
Kaplan M, Ghosal D, Subramanian P, Oikonomou CM, Kjaer A, Pirbadian S, Ortega DR, Briegel A, El-Naggar MY, Jensen GJ
Rapid tilt-series acquisition for electron cryotomography
Journal of Structural Biology
Chreifi G*, Chen S*, Metskas LA, Kaplan M, Jensen GJ
Chreifi G*, Chen S*, Metskas LA, Kaplan M, Jensen GJ
2018
Programmed secretion arrest and receptor-triggered toxin export during antibacterial contact-dependent growth inhibition
Cell
Ruhe ZC*, Subramanian P*, Song K*, Nguyen JY, Stevens TA, Low DA, Jensen GJ+, Hayes CS+
Ruhe ZC*, Subramanian P*, Song K*, Nguyen JY, Stevens TA, Low DA, Jensen GJ+, Hayes CS+
Three-dimensional analysis of mitochondrial crista ultrastructure in a patient with Leigh Syndrome by in situ cryoelectron tomography
iScience
Siegmund SE, Grassucci R, Carter SD, Barca E, Farino ZJ, Juanola-Falgarona M, Zhang P, Tanji K, Hirano M, Schon EA, Frank J, Freyberg Z
Siegmund SE, Grassucci R, Carter SD, Barca E, Farino ZJ, Juanola-Falgarona M, Zhang P, Tanji K, Hirano M, Schon EA, Frank J, Freyberg Z
Selective permeability of carboxysome shell pores to anionic molecules
Journal of Physical Chemistry B
Mahinthichaichan P*, Morris DM*, Wang Y, Jensen GJ+, Tajkhorshid E+
Mahinthichaichan P*, Morris DM*, Wang Y, Jensen GJ+, Tajkhorshid E+
Nutrient transport suggests an evolutionary basis for charged archaeal surface layer proteins
ISME Journal
Li P-N, Herrmann J, Tolar BB, Poitevin F, Ramdasi R, Bargar JR, Stahl DA, Jensen GJ, Francis CA+, Wakatsuki S+, van den Bedem H+
Li P-N, Herrmann J, Tolar BB, Poitevin F, Ramdasi R, Bargar JR, Stahl DA, Jensen GJ, Francis CA+, Wakatsuki S+, van den Bedem H+
Coarse-grained simulations of actomyosin rings point to a nodeless model involving both unipolar and bipolar myosins
Molecular Biology of the Cell
Nguyen LT, Swulius MT, Aich S, Mishra M, Jensen GJ
Nguyen LT, Swulius MT, Aich S, Mishra M, Jensen GJ
In vivo structures of the Helicobacter pylori cag type IV secretion system
Cell Reports
Chang Y-W*, Shaffer CL*, Rettberg LA, Ghosal D, Jensen GJ
Chang Y-W*, Shaffer CL*, Rettberg LA, Ghosal D, Jensen GJ
Ultrastructure of Shewanella oneidensis MR-1 nanowires revealed by electron cryotomography
PNAS
Subramanian P*, Pirbadian S*, El-Naggar MY+, Jensen GJ+
Subramanian P*, Pirbadian S*, El-Naggar MY+, Jensen GJ+
Electron cryotomography of Mycoplasma pneumoniae mutants correlates terminal organelle architectural features and function
Molecular Microbiology
Krause DC+, Chen S, Shi J, Jensen A, Sheppard ES, Jensen GJ
Krause DC+, Chen S, Shi J, Jensen A, Sheppard ES, Jensen GJ
Structure of the fission yeast actomyosin ring during constriction
PNAS
Swulius MT*, Nguyen LT*, Ladinsky MS, Ortega DR, Aich S, Mishra M, Jensen GJ
Swulius MT*, Nguyen LT*, Ladinsky MS, Ortega DR, Aich S, Mishra M, Jensen GJ
2017
Comment: The development of cryo-EM and how it has advanced microbiology
Nature Microbiology
Oikonomou CM, Jensen GJ
Oikonomou CM, Jensen GJ
Assigning chemoreceptors to chemosensory pathways in Pseudomonas aeruginosa
PNAS
Ortega DR*, Fleetwood AD*, Krell T, Harwood CS, Jensen GJ, Zhulin IB
Ortega DR*, Fleetwood AD*, Krell T, Harwood CS, Jensen GJ, Zhulin IB
Distinguishing signal from autofluorescence in cryogenic correlated light and electron microscopy of mammalian cells
Journal of Structural Biology
Carter SD*, Mageswaran SK*, Farino ZJ, Mamede JI, Oikonomou CM, Hope TJ, Freyberg Z+, Jensen GJ+
Carter SD*, Mageswaran SK*, Farino ZJ, Mamede JI, Oikonomou CM, Hope TJ, Freyberg Z+, Jensen GJ+
Nitrosopumilus maritimus gen. nov., sp. nov., Nitrosopumilus cobalaminigenes sp. nov., Nitrosopumilus oxyclinae sp. nov., and Nitrosopumilus ureiphilus sp. nov., four marine ammonia-oxidizing archaea of the phylum Thaumarchaeota
International Journal of Systematic & Evolutionary Microbiology
Qin W, Heal KR, Ramdasi R, Kobelt JN, Martens-Habbena W, Bertagnolli AD, Amin SA, Walker CB, Urakawa H, Könneke M, Devol AH, Moffett JW, Armbrust EV, Jensen GJ, Ingalls AE, Stahl DA
Qin W, Heal KR, Ramdasi R, Kobelt JN, Martens-Habbena W, Bertagnolli AD, Amin SA, Walker CB, Urakawa H, Könneke M, Devol AH, Moffett JW, Armbrust EV, Jensen GJ, Ingalls AE, Stahl DA
FtsEX-mediated regulation of the final stages of cell division reveals morphogenetic plasticity in Caulobacter crescentus
PLoS Genetics
Meier EL, Daitch AK, Yao Q, Bhargava A, Jensen GJ, Goley ED
Meier EL, Daitch AK, Yao Q, Bhargava A, Jensen GJ, Goley ED
LytM factors affect the recruitment of autolysins to the cell division site in Caulobacter crescentus
Molecular Microbiology
Zielińska A*, Billini M*, Möll A, Kremer K, Briegel A, Martinez AI, Jensen GJ, Thanbichler M
Zielińska A*, Billini M*, Möll A, Kremer K, Briegel A, Martinez AI, Jensen GJ, Thanbichler M
Best practices for managing large cryoEM facilities
Journal of Structural Biology
Alewijnse B, Ashton AW, Chambers MG, Chen S, Cheng A, Ebrahim M, Eng E, Hagen WJH, Koster AJ, Lopez CS, Lukoyanova N, Ortega J, Renault L, Reyntjens S, Rice WJ, Scapin G, Schrijver R, Siebert A, Stagg SM, Grum-Tokars V, Wright ER, Wu S, Yu Z, Zhou ZH, Carragher B, Potter CS
Alewijnse B, Ashton AW, Chambers MG, Chen S, Cheng A, Ebrahim M, Eng E, Hagen WJH, Koster AJ, Lopez CS, Lukoyanova N, Ortega J, Renault L, Reyntjens S, Rice WJ, Scapin G, Schrijver R, Siebert A, Stagg SM, Grum-Tokars V, Wright ER, Wu S, Yu Z, Zhou ZH, Carragher B, Potter CS
Photon-induced near-field electron microscopy (PINEM) of eukaryotic cells
Angewandte Chemie International Edition
Kaplan M, Yoo BK, Tang J+, Karam T, Liao B, Majumdar B, Baltimore D, Jensen G+, Zewail A
Kaplan M, Yoo BK, Tang J+, Karam T, Liao B, Majumdar B, Baltimore D, Jensen G+, Zewail A
Morphology of the archaellar motor and associated cytoplasmic cone in Thermococcus kodakaraensis
EMBO Reports
Briegel A, Oikonomou CM, Chang Y-W, Kjaer A, Huang AN, Kim KW, Ghosal D, Nguyen HH, Kenny D, Ogorzalek Loo RR, Gunsalus RP, Jensen GJ
Briegel A, Oikonomou CM, Chang Y-W, Kjaer A, Huang AN, Kim KW, Ghosal D, Nguyen HH, Kenny D, Ogorzalek Loo RR, Gunsalus RP, Jensen GJ
Polar delivery of Legionella type IV secretion system substrates is essential for virulence
PNAS
Jeong KC, Ghosal D, Chang Y-W, Jensen GJ, Vogel JP
Jeong KC, Ghosal D, Chang Y-W, Jensen GJ, Vogel JP
Uncharacterized bacterial structures revealed by electron cryotomography
Journal of Bacteriology
Dobro MJ, Oikonomou CM, Piper A, Cohen J, Guo K, Jensen T, Tadayon J, Donermeyer J, Park Y, Solis BA, Kjaer A, Jewett AI, McDowall AW, Chen S, Chang Y-W, Shi J, Subramanian P, Iancu CV, Li Z, Briegel A, Tocheva EI, Pilhofer M, Jensen GJ
Dobro MJ, Oikonomou CM, Piper A, Cohen J, Guo K, Jensen T, Tadayon J, Donermeyer J, Park Y, Solis BA, Kjaer A, Jewett AI, McDowall AW, Chen S, Chang Y-W, Shi J, Subramanian P, Iancu CV, Li Z, Briegel A, Tocheva EI, Pilhofer M, Jensen GJ
The Structure, Function and Roles of the Archaeal ESCRT Apparatus
Subcellular Biochemistry
Samson RY, Dobro MJ, Jensen GJ, Bell SD
Samson RY, Dobro MJ, Jensen GJ, Bell SD
In vivo structures of an intact type VI secretion system revealed by electron cryotomography
EMBO Reports
Chang Y-W, Rettberg LA, Ortega DR, Jensen GJ
Chang Y-W, Rettberg LA, Ortega DR, Jensen GJ
Short FtsZ filaments can drive asymmetric cell envelope constriction at the onset of bacterial cytokinesis
The EMBO Journal
Yao Q, Jewett AI, Chang Y-W, Oikonomou CM, Beeby M, Iancu CV, Briegel A, Ghosal D, Jensen GJ
Yao Q, Jewett AI, Chang Y-W, Oikonomou CM, Beeby M, Iancu CV, Briegel A, Ghosal D, Jensen GJ
Cellular Electron Cryotomography: Toward Structural Biology In Situ
Annual Review of Biochemistry
Oikonomou CM, Jensen GJ
Oikonomou CM, Jensen GJ
Giant viruses with an expanded complement of translation system components
Science
Schulz F+, Yutin N, Ivanova NN, Ortega DR, Lee TK, Vierheilig J, Daims H, Horn M, Wagner M, Jensen GJ, Kyrpides NC, Koonin EV+, Woyke T+
Schulz F+, Yutin N, Ivanova NN, Ortega DR, Lee TK, Vierheilig J, Daims H, Horn M, Wagner M, Jensen GJ, Kyrpides NC, Koonin EV+, Woyke T+
The variable internal structure of the Mycoplasma penetrans attachment organelle revealed by biochemical and microscopic analyses: implications for attachment organelle mechanism and evolution
Journal of Bacteriology
Distelhorst SL, Jurkovic DA, Shi J, Jensen GJ, Balish MF
Distelhorst SL, Jurkovic DA, Shi J, Jensen GJ, Balish MF
Structure of the Legionella Dot/Icm type IV secretion system in situ by electron cryotomography
EMBO Reports
Ghosal D, Chang Y-W, Jeong KC, Vogel JP, Jensen GJ
Ghosal D, Chang Y-W, Jeong KC, Vogel JP, Jensen GJ
Progress and Potential of Electron Cryotomography as Illustrated by Its Application to Bacterial Chemoreceptor Arrays
Annual Review of Biophysics
Briegel A, Jensen G
Briegel A, Jensen G
Polyphosphate granule biogenesis is temporally and functionally tied to cell cycle exit during starvation in Pseudomonas aeruginosa
PNAS
Racki LR, Tocheva EI, Dieterle MG, Sullivan MC, Jensen GJ, Newman DK
Racki LR, Tocheva EI, Dieterle MG, Sullivan MC, Jensen GJ, Newman DK
Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography
Nature Microbiology
Chang Y-W, Kjaer A, Ortega DR, Kovacikova G, Sutherland JA, Rettberg LA, Taylor RK, Jensen GJ
Chang Y-W, Kjaer A, Ortega DR, Kovacikova G, Sutherland JA, Rettberg LA, Taylor RK, Jensen GJ
2016
Dynamics of the peptidoglycan biosynthetic machinery in the stalked budding bacterium Hyphomonas neptunium
Molecular Microbiology
Cserti E, Rosskopf S, Chang Y-W, Eisheuer S, Selter L, Shi J, Regh C, Koert U, Jensen GJ, Thanbichler M
Cserti E, Rosskopf S, Chang Y-W, Eisheuer S, Selter L, Shi J, Regh C, Koert U, Jensen GJ, Thanbichler M
Electron cryotomography
Methods in Microbiology
Oikonomou CM, Swulius MT, Briegel A, Beeby M, Yao Q, Chang Y-W, Jensen GJ
Oikonomou CM, Swulius MT, Briegel A, Beeby M, Yao Q, Chang Y-W, Jensen GJ
Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop
PNAS
Wang H, Cohen AA, Galimidi RP, Gristick HB, Jensen GJ, Bjorkman PJ
Wang H, Cohen AA, Galimidi RP, Gristick HB, Jensen GJ, Bjorkman PJ
Starvation and recovery in the deep-sea methanotroph Methyloprofundus sedimenti
Molecular Microbiology
Tavormina PL+, Kellermann MY, Antony CP, Tocheva E, Dalleska N, Jensen AJ, Valentine DL, Hinrichs KU, Jensen G, Dubilier N, Orphan VJ
Tavormina PL+, Kellermann MY, Antony CP, Tocheva E, Dalleska N, Jensen AJ, Valentine DL, Hinrichs KU, Jensen G, Dubilier N, Orphan VJ
Chemotaxis cluster 1 proteins form cytoplasmic arrays in Vibrio cholerae and are stabilized by a double signaling domain receptor DosM
PNAS
Briegel A+, Ortega DR, Mann P, Kjaer A, Ringgaard S, Jensen GJ+
Briegel A+, Ortega DR, Mann P, Kjaer A, Ringgaard S, Jensen GJ+
Sporulation, bacterial cell envelopes, and the origin of life
Nature Reviews Microbiology
Tocheva EI+, Ortega DR, Jensen GJ+
Tocheva EI+, Ortega DR, Jensen GJ+
Coarse-Grained Molecular Dynamics Simulations of the Bacterial Cell Wall
Methods in Molecular Biology
Nguyen LT, Gumbart JC, Jensen GJ
Nguyen LT, Gumbart JC, Jensen GJ
Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids
eLife
Li YL*, Chandrasekaran V*, Carter SD, Woodward CL, Christensen DE, Dryden KA, Pornillos O, Yeager M, Ganser-Pornillos BK*, Jensen GJ*, Sundquist WI*
Li YL*, Chandrasekaran V*, Carter SD, Woodward CL, Christensen DE, Dryden KA, Pornillos O, Yeager M, Ganser-Pornillos BK*, Jensen GJ*, Sundquist WI*
Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly
Nature Communications
Grime JMA, Dama JF, Ganser-Pornillos BK, Woodward CL, Jensen GJ, Yeager MJ, Voth GA
Grime JMA, Dama JF, Ganser-Pornillos BK, Woodward CL, Jensen GJ, Yeager MJ, Voth GA
Phylogenomic analysis of Candidatus ‘Izimaplasma’ species: free-living representatives from a Tenericutes clade found in methane seeps
ISME Journal
Skennerton CT+, Haroon MF, Briegel A, Shi J, Jensen GJ, Tyson GW, Orphan VJ
Skennerton CT+, Haroon MF, Briegel A, Shi J, Jensen GJ, Tyson GW, Orphan VJ
Diverse high-torque bacterial flagellar motors assemble wider stator rings using a conserved protein scaffold
PNAS
Beeby M, Ribardo DA, Brennan CA, Ruby EG, Jensen GJ, Hendrixson DR
Beeby M, Ribardo DA, Brennan CA, Ruby EG, Jensen GJ, Hendrixson DR
Architecture of the type IVa pilus machine
Science
Chang Y-W, Rettberg LA, Treuner-Lange A, Iwasa J, Sogaard-Andersen L, Jensen GJ
Chang Y-W, Rettberg LA, Treuner-Lange A, Iwasa J, Sogaard-Andersen L, Jensen GJ
A new view into prokaryotic cell biology from electron cryotomography
Nature Reviews Microbiology
Oikonomou CM, Chang Y-W, Jensen GJ
Oikonomou CM, Chang Y-W, Jensen GJ
Dynamic Remodeling of the Magnetosome Membrane Is Triggered by the Initiation of Biomineralization
MBio
Cornejo E, Subramanian P, Li Z, Jensen GJ, Komeili A
Cornejo E, Subramanian P, Li Z, Jensen GJ, Komeili A
2015
Coarse-grained simulations of bacterial cell wall growth reveal that local coordination alone can be sufficient to maintain rod shape
PNAS
Nguyen LT, Gumbart JC, Beeby M, Jensen GJ
Nguyen LT, Gumbart JC, Beeby M, Jensen GJ
The Caltech Tomography Database and Automatic Processing Pipeline
Journal of Structural Biology
Ding HJ, Oikonomou, CM, Jensen GJ
Ding HJ, Oikonomou, CM, Jensen GJ
Direct visualization of vaults within intact cells by electron cryo-tomography
Cellular and Molecular Life Sciences
Woodward CL, Mendonça LM, Jensen GJ
Woodward CL, Mendonça LM, Jensen GJ
Structural conservation of chemotaxis machinery across Archaea and Bacteria
Environmental Microbiology Reports
Briegel A, Ortega DR, Huang AN, Oikonomou CM, Gunsalus RP, Jensen GJ
Briegel A, Ortega DR, Huang AN, Oikonomou CM, Gunsalus RP, Jensen GJ
Electron cryotomography studies of maturing HIV-1 particles reveal the assembly pathway of the viral core
Journal of Virology
Woodward CL, Cheng SN, Jensen GJ
Woodward CL, Cheng SN, Jensen GJ
Streptomyces: a screening tool for bacterial cell division inhibitors
Journal of Biomolecular Screening
Jani C, Tocheva EI, McAuley S, Craney A, Jensen GJ, Nodwell J
Jani C, Tocheva EI, McAuley S, Craney A, Jensen GJ, Nodwell J
2014
Ultrastructure and complex polar architecture of the human pathogen Campylobacter jejuni
Microbiology Open
Müller A, Beeby M, McDowall AW, Chow J, Jensen GJ, Clemons WM Jr.
Müller A, Beeby M, McDowall AW, Chow J, Jensen GJ, Clemons WM Jr.
Correlated cryogenic photoactivated localization microscopy and cryo-electron tomography
Nature Methods
Chang YW, Chen S, Tocheva EI, Treuner-Lange A, Löbach S, Søgaard-Andersen L, Jensen GJ
Chang YW, Chen S, Tocheva EI, Treuner-Lange A, Löbach S, Søgaard-Andersen L, Jensen GJ
Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling
eLife
Briegel A, Ladinsky MS, Oikonomou C, Jones CW, Harris MJ, Fowler DJ, Chang YW, Thompson LK, Armitage JP, Jensen GJ
Briegel A, Ladinsky MS, Oikonomou C, Jones CW, Harris MJ, Fowler DJ, Chang YW, Thompson LK, Armitage JP, Jensen GJ
Escherichia coli peptidoglycan structure and mechanics as predicted by atomic-scale simulations
PLOS Computational Biology
Gumbart JC+, Beeby M, Jensen GJ, Roux B+
Gumbart JC+, Beeby M, Jensen GJ, Roux B+
New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography
Biochemistry
Briegel A, Wong ML, Hodges HL, Oikonomou CM, Piasta KN, Harris MJ, Fowler DJ, Thompson LK, Falke JJ, Kiessling LL, Jensen GJ
Briegel A, Wong ML, Hodges HL, Oikonomou CM, Piasta KN, Harris MJ, Fowler DJ, Thompson LK, Falke JJ, Kiessling LL, Jensen GJ
Structure and expression of propanediol utilization microcompartments in Acetonema longum
Journal of Bacteriology
Tocheva EI, Matson EG, Cheng SN, Chen WG, Leadbetter JR, Jensen GJ
Tocheva EI, Matson EG, Cheng SN, Chen WG, Leadbetter JR, Jensen GJ
Marine tubeworm metamorphosis induced by arrays of bacterial phage tail-like structures
Science
Shikuma NJ*, Pilhofer M*, Weiss GL, Hadfield MG+, Jensen GJ+, Newman DK+
Shikuma NJ*, Pilhofer M*, Weiss GL, Hadfield MG+, Jensen GJ+, Newman DK+
2013
Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ
Nature Communications
Pilhofer M*, Aistleitner K*, Biboy J, Gray J, Kuru E, Hall E, Brun YV, VanNieuwenhze MS, Vollmer W, Horn M+, Jensen GJ+
Pilhofer M*, Aistleitner K*, Biboy J, Gray J, Kuru E, Hall E, Brun YV, VanNieuwenhze MS, Vollmer W, Horn M+, Jensen GJ+
Architecture and host interface of environmental chlamydiae revealed by electron cryotomography
Environmental Microbiology
Pilhofer M*, Aistleitner K*, Ladinsky MS, König L, Horn M+, Jensen GJ+
Pilhofer M*, Aistleitner K*, Ladinsky MS, König L, Horn M+, Jensen GJ+
Chromatin in a marine picoeukaryote is a disordered assemblage of nucleosomes
Chromosoma
Gan L+, Ladinsky MS, Jensen GJ
Gan L+, Ladinsky MS, Jensen GJ
Polyphosphate storage during sporulation in the gram-negative bacterium Acetonema longum
Journal of Bacteriology
Tocheva EI, Dekas AE, McGlynn SE, Morris D, Orphan VJ, Jensen GJ
Tocheva EI, Dekas AE, McGlynn SE, Morris D, Orphan VJ, Jensen GJ
The mobility of two kinase domains in the Escherichia coli chemoreceptor array varies with signalling state
Molecular Microbiology
Briegel A, Ames P, Gumbart JC, Oikonomou CM, Parkinson JS, Jensen GJ
Briegel A, Ames P, Gumbart JC, Oikonomou CM, Parkinson JS, Jensen GJ
Electron cryotomography of ESCRT assemblies and dividing Sulfolobus cells suggests that spiraling filaments are involved in membrane scission
Molecular Biology of the Cell
Dobro MJ, Samson RY, Yu Z, McCullough J, Ding HJ, Chong PL, Bell SD, Jensen GJ
Dobro MJ, Samson RY, Yu Z, McCullough J, Ding HJ, Chong PL, Bell SD, Jensen GJ
The challenge of determining handedness in electron tomography and the use of DNA origami gold nanoparticle helices as molecular standards
Journal of Structural Biology
Briegel A*, Pilhofer M*, Mastronarde DN, Jensen GJ
Briegel A*, Pilhofer M*, Mastronarde DN, Jensen GJ
Architecture and assembly of the Gram-positive cell wall
Molecular Microbiology
Beeby M, Gumbart JC, Roux B, Jensen GJ
Beeby M, Gumbart JC, Roux B, Jensen GJ
Peptidoglycan transformations during Bacillus subtilis sporulation
Molecular Microbiology
Tocheva EI, López-Garrido J, Hughes HV, Fredlund J, Kuru E, Vannieuwenhze MS, Brun YV, Pogliano K, Jensen GJ
Tocheva EI, López-Garrido J, Hughes HV, Fredlund J, Kuru E, Vannieuwenhze MS, Brun YV, Pogliano K, Jensen GJ
Architecture of the major component of the type III secretion system export apparatus
Nature Structural and Molecular Biology
Abrusci P, Vergara-Irigaray M, Johnson S, Beeby MD, Hendrixson DR, Roversi P, Friede ME, Deane JE, Jensen GJ, Tang CM, Lea SM
Abrusci P, Vergara-Irigaray M, Johnson S, Beeby MD, Hendrixson DR, Roversi P, Friede ME, Deane JE, Jensen GJ, Tang CM, Lea SM
Unclosed HIV-1 capsids suggest a curled sheet model of assembly
Journal of Molecular Biology
Yu Z*, Dobro MJ*, Woodward CL, Levandovsky A, Danielson CM, Sandrin V, Shi J, Aiken C, Zandi R, Hope TJ, Jensen GJ
Yu Z*, Dobro MJ*, Woodward CL, Levandovsky A, Danielson CM, Sandrin V, Shi J, Aiken C, Zandi R, Hope TJ, Jensen GJ
2012
Data management challenges in three-dimensional EM
Nature Structural and Molecular Biology
Patwardhan A, Carazo JM, Carragher B, Henderson R, Heymann JB, Hill E, Jensen GJ, Lagerstedt I, Lawson CL, Ludtke SJ, Mostronarde D, Moore WJ, Roseman A, Rosenthal P, Sorzano CO, Sanz-Garcia E, Scheres SH, Subramaniam S, Westbrook J, Winn M, Swedlow JR+, Kleywegt GJ+
Patwardhan A, Carazo JM, Carragher B, Henderson R, Heymann JB, Hill E, Jensen GJ, Lagerstedt I, Lawson CL, Ludtke SJ, Mostronarde D, Moore WJ, Roseman A, Rosenthal P, Sorzano CO, Sanz-Garcia E, Scheres SH, Subramaniam S, Westbrook J, Winn M, Swedlow JR+, Kleywegt GJ+
General protein diffusion barriers create compartments within bacterial cells
Cell
Schlimpert S*, Klein EA*, Briegel A, Hughes V, Kahnt J, Bolte K, Maier UG, Brun YV, Jensen GJ, Gitai Z, Thanbichler M
Schlimpert S*, Klein EA*, Briegel A, Hughes V, Kahnt J, Bolte K, Maier UG, Brun YV, Jensen GJ, Gitai Z, Thanbichler M
The bacterial cytoskeleton: more than twisted filaments
Current Opinion in Cell Biology
Pilhofer M, Jensen GJ
Pilhofer M, Jensen GJ
A multidomain hub anchors the chromosome segregation and chemotactic machinery to the bacterial pole
Genes and Development
Yamaichi Y*, Bruckner R*, Ringgaard S, Möll A, Cameron DE, Briegel A, Jensen GJ, Davis BM, Waldor MK
Yamaichi Y*, Bruckner R*, Ringgaard S, Möll A, Cameron DE, Briegel A, Jensen GJ, Davis BM, Waldor MK
The helical MreB cytoskeleton in Escherichia coli MC1000/pLE7 is an artifact of the N-Terminal yellow fluorescent protein tag
Journal of Bacteriology
Swulius MT, Jensen GJ
Swulius MT, Jensen GJ
Type VI secretion requires a dynamic contractile phage tail-like structure
Nature
Basler M*, Pilhofer M*, Henderson GP, Jensen GJ+, Mekalanos JJ+
Basler M*, Pilhofer M*, Henderson GP, Jensen GJ+, Mekalanos JJ+
Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins
PNAS
Briegel A*, Li X*, Bilwes AM, Hughes KT, Jensen GJ+, Crane BR+
Briegel A*, Li X*, Bilwes AM, Hughes KT, Jensen GJ+, Crane BR+
Growth and localization of polyhydroxybutyrate granules in Ralstonia eutropha
Journal of Bacteriology
Beeby M, Cho M, Stubbe J, Jensen GJ
Beeby M, Cho M, Stubbe J, Jensen GJ
2011
Microtubules in bacteria: Ancient tubulins build a five-protofilament homolog of the eukaryotic cytoskeleton
PLoS Biology
Pilhofer M+, Ladinsky MS, McDowall AW, Petroni G, Jensen GJ+
Pilhofer M+, Ladinsky MS, McDowall AW, Petroni G, Jensen GJ+
Activated chemoreceptor arrays remain intact and hexagonally packed
Molecular Microbiology
Briegel A, Beeby M, Thanbichler M, Jensen GJ
Briegel A, Beeby M, Thanbichler M, Jensen GJ
Peptidoglycan remodeling and conversion of an inner membrane into an outer membrane during sporulation
Cell
Tocheva EI, Matson EG, Morris DM, Moussavi F, Leadbetter JR, Jensen GJ
Tocheva EI, Matson EG, Morris DM, Moussavi F, Leadbetter JR, Jensen GJ
Nanopods: a new bacterial structure and mechanism for deployment of outer membrane vesicles
PLoS
Shetty A, Chen S, Tocheva EI, Jensen GJ, Hickey WJ
Shetty A, Chen S, Tocheva EI, Jensen GJ, Hickey WJ
Structural diversity of bacterial flagellar motors
The EMBO Journal
Chen S*, Beeby M*, Murphy GE, Leadbetter JR, Hendrixson DR, Briegel A, Li Z, Shi J, Tocheva EI, Müller A, Dobro MJ, Jensen GJ
Chen S*, Beeby M*, Murphy GE, Leadbetter JR, Hendrixson DR, Briegel A, Li Z, Shi J, Tocheva EI, Müller A, Dobro MJ, Jensen GJ
Alternative mechanism for bacteriophage adsorption to the motile bacterium Caulobacter crescentus
PNAS
Guerrero-Ferreira RC, Viollier PH, Ely B, Poindexter JS, Georgieva M, Jensen GJ, Wright ER
Guerrero-Ferreira RC, Viollier PH, Ely B, Poindexter JS, Georgieva M, Jensen GJ, Wright ER
Long helical filaments are not seen encircling cells in electron cryotomograms of rod-shaped bacteria
Biochemical and Biophysical Research Communications
Swulius MT, Chen S, Jane Ding H, Li Z, Briegel A, Pilhofer M, Tocheva EI, Lybarger SR, Johnson TL, Sandkvist M, Jensen GJ
Swulius MT, Chen S, Jane Ding H, Li Z, Briegel A, Pilhofer M, Tocheva EI, Lybarger SR, Johnson TL, Sandkvist M, Jensen GJ
2010
In vivo assembly of an archaeal virus studied with whole-cell electron cryotomography
Structure
Fu CY, Wang K, Gan L, Lanman J, Khayat R, Young MJ, Jensen GJ, Doerschuk PC, Johnson JE
Fu CY, Wang K, Gan L, Lanman J, Khayat R, Young MJ, Jensen GJ, Doerschuk PC, Johnson JE
Correcting for the Ewald sphere in high-resolution single-particle reconstructions
Methods in Enzymology
Leong PA, Yu X, Zhou ZH, Jensen GJ
Leong PA, Yu X, Zhou ZH, Jensen GJ
A description of the instruments, samples, protocols, and analyses that belong to the growing field of cryo-EM
Methods in Enzymology
Jensen GJ
Jensen GJ
Correlated light and electron cryo-microscopy
Methods in Enzymology
Briegel A, Chen S, Koster AJ, Plitzko JM, Schwartz CL, Jensen GJ
Briegel A, Chen S, Koster AJ, Plitzko JM, Schwartz CL, Jensen GJ
Plunge freezing for electron cryomicroscopy
Methods in Enzymology
Dobro MJ, Melanson LA, Jensen GJ, McDowall AW
Dobro MJ, Melanson LA, Jensen GJ, McDowall AW
Bacterial TEM: new insights from cryo-microscopy
Methods in Cell Biology
Pilhofer M, Ladinsky MS, McDowall AW, Jensen GJ
Pilhofer M, Ladinsky MS, McDowall AW, Jensen GJ
The metabolic enzyme CTP synthase forms cytoskeletal filaments
Nature Cell Biology
Ingerson-Mahar M, Briegel A, Werner JN, Jensen GJ, Gitai Z
Ingerson-Mahar M, Briegel A, Werner JN, Jensen GJ, Gitai Z
DipM, a new factor required for peptidoglycan remodelling during cell division in Caulobacter crescentus
Molecular Microbiology
Möll A, Schlimpert S, Briegel A, Jensen GJ, Thanbichler M
Möll A, Schlimpert S, Briegel A, Jensen GJ, Thanbichler M
Electron cryotomography of bacterial cells
JoVE
Chen S, McDowall A, Dobro MJ, Briegel A, Ladinsky M, Shi J, Tocheva EI, Beeby M, Pilhofer M, Ding HJ, Li Z, Gan L, Morris DM, Jensen GJ
Chen S, McDowall A, Dobro MJ, Briegel A, Ladinsky M, Shi J, Tocheva EI, Beeby M, Pilhofer M, Ding HJ, Li Z, Gan L, Morris DM, Jensen GJ
Mutations in the Lipopolysaccharide biosynthesis pathway interfere with crescentin-mediated cell curvature in Caulobacter crescentus
Journal of Bacteriology
Cabeen MT*, Murolo MA*, Briegel A, Bui NK, Vollmer W, Ausmees N, Jensen GJ, Jacobs-Wagner C
Cabeen MT*, Murolo MA*, Briegel A, Bui NK, Vollmer W, Ausmees N, Jensen GJ, Jacobs-Wagner C
Bactofilins, a ubiquitous class of cytoskeletal proteins mediating polar localization of a cell wall synthase in Caulobacter crescentus
The EMBO Journal
Kühn J, Briegel A, Mörschel E, Kahnt J, Leser K, Wick S, Jensen GJ, Thanbichler M
Kühn J, Briegel A, Mörschel E, Kahnt J, Leser K, Wick S, Jensen GJ, Thanbichler M
Organization, structure, and assembly of alpha-carboxysomes determined by electron cryotomography of intact cells
Journal of Molecular Biology
Iancu CV*, Morris DM*, Dou Z, Heinhorst S, Cannon GC, Jensen GJ
Iancu CV*, Morris DM*, Dou Z, Heinhorst S, Cannon GC, Jensen GJ
2009
Universal architecture of bacterial chemoreceptor arrays
PNAS
Briegel A, Ortega DR, Tocheva EI, Wuichet K, Li Z, Chen S, Müller A, Iancu CV, Murphy GE, Dobro MJ, Zhulin IB, Jensen GJ
Briegel A, Ortega DR, Tocheva EI, Wuichet K, Li Z, Chen S, Müller A, Iancu CV, Murphy GE, Dobro MJ, Zhulin IB, Jensen GJ
Nanogold as a specific marker for electron cryotomography
Microscopy and Microanalysis
He Y, Jensen GJ, Bjorkman PJ
He Y, Jensen GJ, Bjorkman PJ
Electron cryotomography: a new view into microbial ultrastructure
Current Opinion in Microbiology
Li Z, Jensen GJ
Li Z, Jensen GJ
Fully automated, sequential tilt-series acquisition with Leginon
Journal of Structural Biology
Suloway C, Shi J, Cheng A, Pulokas J, Carragher B, Potter CS, Zheng SQ, Agard DA, Jensen GJ
Suloway C, Shi J, Cheng A, Pulokas J, Carragher B, Potter CS, Zheng SQ, Agard DA, Jensen GJ
Cryo-electron tomography of homophilic adhesion mediated by the neural cell adhesion molecule L1
Structure
He Y, Jensen GJ, Bjorkman PJ
He Y, Jensen GJ, Bjorkman PJ
2008
FcRn-mediated antibody transport across epithelial cells revealed by electron tomography
Nature
He W, Ladinsky MS, Huey-Tubman KE, Jensen GJ, McIntosh JR, Björkman PJ
He W, Ladinsky MS, Huey-Tubman KE, Jensen GJ, McIntosh JR, Björkman PJ
A self-associating protein critical for chromosome attachment, division, and polar organization in caulobacter
Cell
Ebersbach G, Briegel A, Jensen GJ, Jacobs-Wagner C
Ebersbach G, Briegel A, Jensen GJ, Jacobs-Wagner C
Radiation dose reduction and image enhancement in biological imaging through equally-sloped tomography
Journal of Structural Biology
Lee E*, Fahimian BP*, Iancu CV, Suloway C, Murphy GE, Wright ER, Castaño-Díez D, Jensen GJ, Miao J
Lee E*, Fahimian BP*, Iancu CV, Suloway C, Murphy GE, Wright ER, Castaño-Díez D, Jensen GJ, Miao J
Location and architecture of the Caulobacter crescentus chemoreceptor array
Molecular Microbiology
Briegel A, Ding HJ, Li Z, Werner J, Gitai Z, Dias DP, Jensen RB, Jensen GJ
Briegel A, Ding HJ, Li Z, Werner J, Gitai Z, Dias DP, Jensen RB, Jensen GJ
Toward a biomechanical understanding of whole bacterial cells
Annual Review of Biochemistry
Morris DM, Jensen GJ
Morris DM, Jensen GJ
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p
Journal of Molecular Biology
Yu Z, Gonciarz MD, Sundquist WI, Hill CP, Jensen GJ
Yu Z, Gonciarz MD, Sundquist WI, Hill CP, Jensen GJ
Novel ultrastructures of Treponema primitia and their implications for motility
Molecular Microbiology
Murphy GE, Matson EG, Leadbetter JR, Berg HC, Jensen GJ
Murphy GE, Matson EG, Leadbetter JR, Berg HC, Jensen GJ
2007
Tetrasphaera remsis sp. nov., isolated from the Regenerative Enclosed Life Support Module Simulator (REMS) air system
International Journal of Systematic and Evolutionary Microbiology
Osman S, Moissl C, Hosoya N, Briegel A, Mayliraj S, Satomi M, Venkateswaran K
Osman S, Moissl C, Hosoya N, Briegel A, Mayliraj S, Satomi M, Venkateswaran K
The structure of FtsZ filaments in vivo suggests a force-generating role in cell division
The EMBO Journal
Li Z, Trimble MJ, Brun YV, Jensen GJ
Li Z, Trimble MJ, Brun YV, Jensen GJ
3-D ultrastructure of O. tauri: electron cryotomography of an entire eukaryotic cell
PLoS One
Henderson GP, Gan L, Jensen GJ
Henderson GP, Gan L, Jensen GJ
The structure of isolated Synechococcus strain WH8102 carboxysomes as revealed by electron cryotomography
Journal of Molecular Biology
Iancu CV, Ding HJ, Morris DM, Dias DP, Gonzales AD, Martino A, Jensen GJ
Iancu CV, Ding HJ, Morris DM, Dias DP, Gonzales AD, Martino A, Jensen GJ
How electron cryotomography is opening a new window onto prokaryotic ultrastructure
Current Opinion in Structural Biology
Jensen GJ, Briegel A
Jensen GJ, Briegel A
Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells
The EMBO Journal
Wright ER*, Schooler JB*, Ding HJ, Kieffer C, Fillmore C, Sundquist WI, Jensen GJ
Wright ER*, Schooler JB*, Ding HJ, Kieffer C, Fillmore C, Sundquist WI, Jensen GJ
Haloquadratum walsbyi gen. nov., sp. nov., the square haloarchaeon of Walsby, isolated from saltern crystallizers in Australia and Spain
Int'l Journal of Systematic & Evolutionary Microbiology
Burns DG, Janssen PH, Itoh T, Kamekura M, Li Z, Jensen G, Rodriguez-Valera F, Bolhuis H, Dyall-Smith ML
Burns DG, Janssen PH, Itoh T, Kamekura M, Li Z, Jensen G, Rodriguez-Valera F, Bolhuis H, Dyall-Smith ML
2006
In situ structure of the complete Treponema primitia flagellar motor
Nature
Murphy GE, Leadbetter JR, Jensen GJ
Murphy GE, Leadbetter JR, Jensen GJ
Multiple large filament bundles observed in Caulobacter crescentus by electron cryotomography
Molecular Microbiology
Briegel A, Dias DP, Li Z, Jensen RB, Frangakis AS, Jensen GJ
Briegel A, Dias DP, Li Z, Jensen RB, Frangakis AS, Jensen GJ
Electron cryotomography sample preparation using the Vitrobot
Nature Protobols
Iancu CV, Tivol WF, Schooler JB, Dias DP, Henderson GP, Murphy GE, Wright ER, Li Z, Yu Z, Briegel A, Gan L, He Y, Jensen GJ
Iancu CV, Tivol WF, Schooler JB, Dias DP, Henderson GP, Murphy GE, Wright ER, Li Z, Yu Z, Briegel A, Gan L, He Y, Jensen GJ
Three-dimensional structure of Mycoplasma pneumoniae’s attachment organelle and a model for its role in gliding motility
Molecular Microbiology
Henderson GP, Jensen GJ
Henderson GP, Jensen GJ
Rigid, specific, and discrete gold nanoparticle/antibody conjugates
Journal of the American Chemical Society
Ackerson CJ, Jadzinsky PD, Jensen GJ, Kornberg RD
Ackerson CJ, Jadzinsky PD, Jensen GJ, Kornberg RD
Observations on the behavior of vitreous ice at approximately 82 and approximately 12 K
Journal of Structural Biology
Wright ER*, Iancu CV*, Tivol WF, Jensen GJ
Wright ER*, Iancu CV*, Tivol WF, Jensen GJ
A comparison of liquid nitrogen and liquid helium as cryogens for electron cryotomography
Journal of Structural Biology
Iancu CV, Wright ER, Heymann JB, Jensen GJ
Iancu CV, Wright ER, Heymann JB, Jensen GJ
Magnetosomes are cell membrane invaginations organized by the actin-like protein MamK
Science
Komeili A*+, Li Z*, Newman DK, Jensen GJ
Komeili A*+, Li Z*, Newman DK, Jensen GJ
2005
Electron cryotomography of the E. coli pyruvate and 2-oxoglutarate dehydrogenase complexes
Structure
Murphy GE, Jensen GJ
Murphy GE, Jensen GJ
A “flip-flop” rotation stage for routine dual-axis electron cryotomography
Journal of Structural Biology
Iancu CV*, Wright ER*, Benjamin J, Tivol WF, Dias DP, Murphy GE, Morrison RC, Heymann JB, Jensen GJ
Iancu CV*, Wright ER*, Benjamin J, Tivol WF, Dias DP, Murphy GE, Morrison RC, Heymann JB, Jensen GJ
Peach: a simple Perl-based system for distributed computation and its application to cryo-EM data processing
Structure
Leong PA*, Heymann JB*, Jensen GJ
Leong PA*, Heymann JB*, Jensen GJ
Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography
Journal of Molecular Biology
Benjamin J, Ganser-Pornillos BK, Tivol WF, Sundquist WI, Jensen GJ
Benjamin J, Ganser-Pornillos BK, Tivol WF, Sundquist WI, Jensen GJ