HIV Structural Biology

Correlated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivo

March 16, 2023 01:15 PM

PNAS

Carter SD, Mamede JI, Hope TJ, Jensen GJ

Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop

March 14, 2023 02:07 PM

PNAS

Wang H, Cohen AA, Galimidi RP, Gristick HB, Jensen GJ, Bjorkman PJ

Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids

March 14, 2023 02:03 PM

eLife

Li YL*, Chandrasekaran V*, Carter SD, Woodward CL, Christensen DE, Dryden KA, Pornillos O, Yeager M, Ganser-Pornillos BK*, Jensen GJ*, Sundquist WI*

Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly

March 14, 2023 02:02 PM

Nature Communications

Grime JMA, Dama JF, Ganser-Pornillos BK, Woodward CL, Jensen GJ, Yeager MJ, Voth GA

Electron cryotomography studies of maturing HIV-1 particles reveal the assembly pathway of the viral core

March 14, 2023 01:49 PM

Journal of Virology

Woodward CL, Cheng SN, Jensen GJ

Unclosed HIV-1 capsids suggest a curled sheet model of assembly

March 14, 2023 01:10 PM

Journal of Molecular Biology

Yu Z*, Dobro MJ*, Woodward CL, Levandovsky A, Danielson CM, Sandrin V, Shi J, Aiken C, Zandi R, Hope TJ, Jensen GJ

Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p

March 09, 2023 01:52 PM

Journal of Molecular Biology

Yu Z, Gonciarz MD, Sundquist WI, Hill CP, Jensen GJ

Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells

March 08, 2023 02:11 PM

The EMBO Journal

Wright ER*, Schooler JB*, Ding HJ, Kieffer C, Fillmore C, Sundquist WI, Jensen GJ

Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography

March 08, 2023 12:59 PM

Journal of Molecular Biology

Benjamin J, Ganser-Pornillos BK, Tivol WF, Sundquist WI, Jensen GJ